|
Y chromosome
The Y chromosome is one of two sex chromosomes in therian mammals and other organisms. The other sex chromosome is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or absence of Y that determines the male or female sex of offspring produced in sexual reproduction. In mammals, the Y chromosome contains the gene SRY, which triggers male development. The DNA in the human Y chromosome is composed of about 62 million base pairs, making it similar in size to chromosome 19. The Y chromosome is passed only from male parent to male offspring. With a 30% difference between humans and chimpanzees, the Y chromosome is one of the fastest-evolving parts of the human genome. The human Y chromosome carries 693 genes, with 107 of these being protein-coding, but some genes are repeated and that makes the number of exclusive protein-coding genes just 42, the numbers are given for telomere-to-telomere CHM13. CCDS only classified 63 out of 10 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
G Banding
G-banding, G banding or Giemsa banding is a technique used in cytogenetics to produce a visible karyotype by staining condensed chromosomes. It is the most common chromosome banding method. It is useful for identifying genetic diseases through the photographic representation of the entire chromosome complement.Speicher, Michael R. and Nigel P. Carter. "The New Cytogenetics: Blurring the Boundaries with Molecular Biology." ''Nature'' Reviews Genetics, Vol 6. Oct 2005. The metaphase chromosomes are treated with trypsin (to partially digest the chromosome) and stained with Giemsa stain. Heterochromatic regions, which tend to be rich with adenine and thymine (AT-rich) DNA and relatively gene-poor, stain more darkly in G-banding. In contrast, less condensed chromatin (Euchromatin)—which tends to be rich with guanine and cytosine ( GC-rich) and more transcriptionally active—incorporates less Giemsa stain, and these regions appear as light bands in G-banding. The pattern of bands are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein-coding Gene
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theophilus Painter
Theophilus Shickel Painter (August 22, 1889 – October 5, 1969) was an American zoologist best known for his work on the structure and function of chromosomes, especially the sex-determination genes X and Y in humans. He was the first to discover that human sex was determined by an X/Y heteromorphic chromosomal pair mechanism.Rudle, Frank H. (2004)Theophilus Painter: First Steps Toward an Understanding of the Human Genome, ''J. Experimental Zoology, 301A'', 375–377. Retrieved 24 Jan. 2022. He also carried out work in identifying genes in fruit flies (''Drosophila''). His work exploited the giant polytene chromosomes in the salivary glands of ''Drosophila'' and other Dipteran larvae. Academic administration Painter joined the faculty at the University of Texas in 1916 and, except for military duty during World War I, stayed there his whole career. He was, in succession, associate professor, professor and distinguished professor of zoology. He served as acting president (1944–1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex-determination System
A sex-determination system is a biological system that determines the development of sexual characteristics in an organism. Most organisms that create their offspring using sexual reproduction have two sexes. In some species there are hermaphrodites. There are also some species that are only one sex due to parthenogenesis, the act of a female reproducing without fertilization. In some species, sex determination is genetic: males and females have different alleles or even different genes that specify their sexual morphology. In animals this is often accompanied by chromosomal differences, generally through combinations of XY, ZW, XO, ZO chromosomes, or haplodiploidy. The sexual differentiation is generally triggered by a main gene (a "sex locus"), with a multitude of other genes following in a domino effect. In other cases, sex of a fetus is determined by environmental variables (such as temperature). The details of some sex-determination systems are not yet fully underst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clarence Erwin McClung
Clarence Erwin McClung (April 5, 1870 – January 17, 1946) was an eminent United States, American zoologist and prairie pioneer cytologist who discovered the role of chromosomes in Sex-determination system, sex-determination. Graduating pharmacy at the University of Kansas in 1892, after a year of teaching he entered the college as a graduate student (A.B.,1896, A.M.,1898, and Ph.D.,1902.) He studied one summer with W.M. Wheeler at the University of Chicago and at his suggestion, studied the spermatogenesis of Ziphidium fasciatum, a long-horned grasshopper; launching his scientific career in the research of chromosomes. McClung took advantage of the great abundance of grasshoppers in Kansas ''"to make them pivotal for cytological study and to found a school of grasshopper cytologists''." Later, the use of Brachystola magna ("Lubber" grasshopper) for cytological studies would spread to laboratories throughout the world, as germ-cells in the testes were very large and easily studi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hermann Henking
Hermann Paul August Otto Henking (16 June 1858 – 28 April 1942) was a German cytologist who discovered the X chromosome in 1890 or 1891. The work was the result of a study in Leipzig of the testicles of the firebug (''Pyrrhocoris apterus''), during which Henking noticed that one chromosome did not take part in meiosis. He named this the ''X element'' because its strange behaviour made him unsure whether it was genuinely a chromosome. It was later named the X chromosome after American cytologist Clarence Erwin McClung Clarence Erwin McClung (April 5, 1870 – January 17, 1946) was an eminent American zoologist and prairie pioneer cytologist who discovered the role of chromosomes in sex-determination. Graduating pharmacy at the University of Kansas in 1892, ... established that it was not only a genuine chromosome but a sex-determining one, though McClung incorrectly guessed that it was the male-determining sex chromosome.David Bainbridge, ''The X in Sex: How the X Chromosom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemiptera
Hemiptera (; ) is an order (biology), order of insects, commonly called true bugs, comprising over 80,000 species within groups such as the cicadas, aphids, planthoppers, leafhoppers, Reduviidae, assassin bugs, Cimex, bed bugs, and shield bugs. They range in size from to around , and share a common arrangement of piercing-sucking Insect mouthparts, mouthparts. The name "true bugs" is often limited to the suborder Heteroptera. Entomologists reserve the term ''bug'' for Hemiptera or Heteroptera,Gilbert Waldbauer. ''The Handy Bug Answer Book.'' Visible Ink, 1998p. 1. which does not include other arthropods or insects of other orders such as Ant, ants, Bee, bees, Beetle, beetles, or Butterfly, butterflies. In some variations of English, all Terrestrial animal, terrestrial arthropods (including non-insect arachnids, and myriapods) also fall under the Colloquialism, colloquial understanding of ''bug''. Many insects with "bug" in their common name, especially in American English, belo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edmund Beecher Wilson
Edmund Beecher Wilson (October 19, 1856 – March 3, 1939) was a pioneering American zoologist and geneticist. He wrote one of the most influential textbooks in modern biology, ''The Cell''. Career Wilson was born in Geneva, Illinois, the son of Isaac G. Wilson, a judge, and his wife, Carioline Clark. He graduated from Yale University in 1878. He earned his Ph.D. at Johns Hopkins in 1881. He was a lecturer at Williams College in 1883–84 and at the Massachusetts Institute of Technology in 1884–85. He served as professor of biology at Bryn Mawr College from 1885 to 1891. In 1888, he was elected as a member to the American Philosophical Society. He spent the balance of his career at Columbia University where he was successively adjunct professor of biology (1891–94), professor of invertebrate zoology (1894–1897), and professor of zoology (from 1897). Wilson is credited as America's first cell biologist. In 1898 he used the similarity in embryos to describe phylogene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mealworm
Mealworms are the larval form of the yellow mealworm beetle, ''Tenebrio molitor'', a species of darkling beetle. Like all holometabolic insects, they go through four life stages: egg, larva, pupa, and adult. Larvae typically measure about or more, whereas adults are generally between in length. Reproduction The mealworm beetle breeds prolifically. Males insert sperm packets with their aedeagus. Within a few days the female burrows into soft ground and lays eggs. Over her lifespan, a female will, on average, lay about 500 eggs. After 4 to 19 days the eggs hatch. During the larval stage, the mealworms feed on vegetation and dead insects and molt between each larval stage, or instar (9 to 20 instars). After the final molt, they pupate. The new pupa is whitish and turns brown over time. After 3 to 30 days, depending on environmental conditions such as temperature, it emerges as an adult beetle. Sex pheromones A sex pheromone released by male mealworms has been identified. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bryn Mawr College
Bryn Mawr College ( ; Welsh: ) is a women's liberal arts college in Bryn Mawr, Pennsylvania. Founded as a Quaker institution in 1885, Bryn Mawr is one of the Seven Sister colleges, a group of elite, historically women's colleges in the United States, and the Tri-College Consortium along with Haverford College and Swarthmore College. The college has an enrollment of about 1,350 undergraduate students and 450 graduate students. It was the first women's college to offer graduate education through a PhD. History Bryn Mawr College is a private women's liberal arts college founded in 1885. The phrase literally means 'large hill' in Welsh. The Graduate School is co-educational. It is named after the town of Bryn Mawr, in which the campus is located, which had been renamed by a representative of the Pennsylvania Railroad. Bryn Mawr was the name of an area estate granted to Rowland Ellis by William Penn in the 1680s. Ellis's former home, also called Bryn Mawr, was a house near Dolge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nettie Stevens
Nettie Maria Stevens (July 7, 1861 – May 4, 1912) was an American geneticist who discovered sex chromosomes. In 1905, soon after the rediscovery of Mendel's paper on genetics in 1900, she observed that male mealworms produced two kinds of sperm, one with a large chromosome and one with a small chromosome. When the sperm with the large chromosome fertilized eggs, they produced female offspring, and when the sperm with the small chromosome fertilized eggs, they produced male offspring. The pair of sex chromosomes that she studied later became known as the X and Y chromosomes. Early life Nettie Maria Stevens was born on July 7, 1861, in Cavendish, Vermont, to Julia (née Adams) and Ephraim Stevens. In 1863, after the death of her mother, her father remarried and the family moved to Westford, Massachusetts.MB Ogilvie, CJ Choquette (1981) "Nettie Maria Stevens (1861–1912): her life and contributions to cytogenetics. ''Proc Amer Phil Soc US'' 125(4):292–311. Her father worked a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
XXYY Syndrome
XXYY syndrome is a sex chromosome anomaly in which males have 2 extra chromosomes, one X and one Y chromosome. Human cells usually contain two sex chromosomes, one from the mother and one from the father. Usually, females have two X chromosomes (XX) and males have one X and one Y chromosome (XY). The appearance of at least one Y chromosome with a properly functioning SRY gene makes a male. Therefore, humans with XXYY are genotypically male. Males with XXYY syndrome have 48 chromosomes instead of the typical 46. This is why XXYY syndrome is sometimes written as 48, XXYY syndrome or 48, XXYY. It affects an estimated one in every 18,000–40,000 male births. Presentation Some signs and symptoms of this condition include: Cause 48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell. Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Nettie Stevens")